Ethanolamine Phospholipid Metabolism in Myelinating Rat Brain
نویسندگان
چکیده
منابع مشابه
Effects of analogles of ethanolamine and choline on phospholipid metabolism in rat hepatocytes.
1. Analogues of ethanolamine and choline were incubated with different labelled precursors of phospholipids and isolated hepatocytes and the effects on phospholipid synthesis were studied. 2. 2-Aminopropan-1-ol and 2-aminobutan-1-ol were the most efficient inhibitors of [(14)C]ethanolamine incorporation into phospholipids, whereas the incorporation of [(3)H]choline was inhibited most extensivel...
متن کاملThe enzymatic conversion of phospholipid ethanolamine to phospholipid choline in rat liver.
It is known from the work of Elwyn et al. (1) that ethanolamine is incorporated as a unit into the choline molecule during the synthesis de novo of this substance. Du Vigneaud et al. (2, 3) showed that at least some of the methyl groups of choline are derived directly from the methyl group of methionine; and in an earlier communication we provided evidence that all the methyl groups originate f...
متن کاملEffects of altered thyroid function on galactosyl diacylglycerol metabolism in myelinating rat brain.
The effects of neonatal thyroid status on the metabolism of the myelin metabolite, galactosyl diacylglycerol, were examined in developing rat brain. There was a 40% reduction in the concentration of monogalactosyl diacylglycerol in the brains of 20and 23-day-old rats which were made hypothyroid at birth. These same animals had a retarded developmental pattern for the galactosyltransferase activ...
متن کاملBrain phospholipid metabolism during ischemia.
Brain Phospholipid Metabolism During Ischemia • Molecular mechanisms accounting for the vulnerability of brain to ischemic damage are incompletely understood. To assess the role of membrane integrity, phospholipid metabolism is investigated in subcellular organelles of brain following varying degrees of ischemia. Global brain ischemia is produced in rabbits by combining hypotension and hypoxia ...
متن کاملUse of 3-aminopropanol as an ethanolamine analogue in the study of phospholipid metabolism in Tetrahymena.
About 50% of the ethanolamine in phosphatidylethanolamine in Tetrahymena is replaced by 3-aminopropan-1-ol when the compound is added to the growth medium. The phosphatidylpropanolamine which is formed is not converted into the corresponding phosphatidylcholine analogue by methylation. There is an increase in phosphatidylcholine formed by the phosphotransferase pathway from free [3H]choline and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Australian Journal of Biological Sciences
سال: 1972
ISSN: 0004-9417
DOI: 10.1071/bi9720125